UNGA 2024 and the AMR HLM:
Reports released in preparation
During the run-up to the HLM (High-Level Meeting) on AMR during UNGA 2024 (the UN General Assembly, September 2024, see the 15 Apr 2023 newsletter for details), I thought it would be useful to have a list of major reports that had been released to inform those discussions. I am sure I am going to miss things (at least initially), so please drop me a note (john.rex@13.43.35.2) if you want to see something added to this list. Thanks, —jr
- Reports (mostly) Focused on AMR related to human health
- Manufacturing
- 05 Jun 2023: Antibiotic Manufacturing Certification
- The AMR Industry Alliance has worked with BSI Standards to develop a certification process for safe discharge during antibiotic manufacturing.
- Press release, website, 25 Sep 2023 newsletter
- 05 Jun 2023: Antibiotic Manufacturing Certification
- Stewardship and Access
- 22 Mar 2021: Stewardship & Access Guide
- From CARB-X, Wellcome, And Partners, this is the definitive guide
- The 22 Mar 2021 newsletter is the best starting point; it also includes a video chat about the new guidelines
- Feb 2024: Equitable & Responsible Access Roadmap
- The AMR Industry Alliance‘s roadmap covers diagnostics, drugs, and procurement.
- The document itself
- 22 Mar 2021: Stewardship & Access Guide
- R&D: Push, Pull, and People
- 07 Sep 2023: Overcoming Resistance
- This one could have been subtitled “How Canada should Pull for new antibiotics”!
- Webpage, report, one-pager on the report, short slide deck, and 8 Sep 2023 newsletter.
- Report author: Canadian Council of Academies (CCA)
- 21 Sep 2023: A New Grand Bargain to Improve the Antimicrobial Market for Human Health
- Tackles the question of “Why would any given group take action to support an antibiotic ecosystem?” from the perspective of High-Income Countries (HICs), Low- and Middle-Income Countries (LMICs), Pharmaceutical companies, and International Organizations.
- Webpage, report, and 5 Nov 2023 newsletter.
- Report author: Center for Global Development (CGD)
- 15 Nov 2023: Value and sustainability of antibiotics as essential tools for the healthcare system and people’s health
- This one could have been subtitled “How Italy should Push and Pull as it takes the 2024 G7 chair“!
- Webpage, full report (in Italian), press release (in English), one-page policy brief (in English), and 7 Dec 2023 newsletter.
- Report author: The European House – Ambrosetti
- 08 Feb 2014: Leaving the Lab: Tracking the Decline in AMR R&D Professionals
- As you can infer from this title, this one summarizes the alarming multi-year decline in the number of active AMR R&D professionals.
- Press release, report, and 8 Feb 2024 newsletter.
- 15 Feb 2024: 2024 AMR Preparedness Index Progress Report
- Updates a 2021 survey on progress on National Action Plans, Push-Pull, Access, Appropriate Use, and Environmental Protection by 11 countries (Brazil, Canada, China, France, Germany, India, Italy, Japan, South Korea, UK, US).
- Press release, report, and 15 Feb 2024 newsletter.
- Report authors: Global Coalition on Aging (GCOA) and the Infectious Diseases Society of America (IDSA)
- 22 Feb 2024: The Economics of Antibiotic Resistance
- A superb tour of way an economist (and hence a Finance Minister) would view AMR as a Market Failure
- Webpage, paper, blog, and 28 Feb 2024 newsletter
- Report authors: For the Center for Global Development (CGD), Anthony McDonnell, Ranil Dissanayake, Katherine Klemperer, Flavio Toxvaerd, and Michael Sharland
- 25 Mar 2024: Effective antibiotics for the Swiss health care system: today and in the future
- This one could have been subtitled “How Switzerland should Push and Pull“!
- Webpage, primary report, and 5 April 2024 newsletter
- Report author: Swiss Roundtable on Antibiotics
- 3 Apr 2024: Towards Specific Commitments and Action in the Response to Antimicrobial Resistance
- Yes, it’s a long title! And, there is a subtitle: Recommendations for consideration by UN Member States in the outcome document of the High-level Meeting on AMR in September 2024
- Webpage, report, and 19 Apr 2024 newsletter
- There is also an important economic study that is used as supportive evidence. It is hard to find, but I do have this link: https://www.amrleaders.org/resources/m/item/annex-to-the-glg-report
- Report author: GLG AMR (Global Leaders Group on Antimicrobial Resistance)
- 23 May 2024: The Lancet Series on Antimicrobial Resistance: The need for sustainable access to effective antibiotics
- A superb collection of papers covering the ideas of (i) Sustainable (ii) Access to (iii) Effective Antibiotics. Look closely at those 3 words: such a good summary … it’s a deep read, but well worth your time!
- Webpage, 23 May 2024 newsletter, Fireside Chat with Ramanan Laxminarayan about the series and its messages
- 12 Aug 2024: UK Subscription model goes live!
- OK, it’s not a report per se but if it were it would be called “Here’s what can be done!”
- The UK Subscription model really does set the pace for the rest of the world to follow
- Webpage, 19 Aug 2024 newsletter
- Aug 2024: Antibacterial pipeline trends and recommendations to enhance research and development
- This policy brief does a good job of briefly (!) outlining 7 key points: the weak pipeline, the issues faced by developers, specific therapeutic gaps, the oral drug gap, the pediatric drug gap, the LMIC gap, and the non-traditional gap
- Webpage, report, 1 Sep 2024 newsletter
- Report author: WHO
- 07 Sep 2023: Overcoming Resistance
- Reports (mostly) focused on agriculture and food chain
- January 2024: Tackling Antimicrobial Resistance in Food and Agriculture
- A global survey of actions being taken by the Quadripartite, the Global Leaders Group, and the various National Action Plans on AMR in agricultural and food systems.
- Webpage, report, and 27 Jan 2024 newsletter.
- Report author: FAO
- About the AMR HLM (High-Level Meeting)
- 23 Jan 2024: Resolution to support an HLM on AMR
- 2 Feb 2024: Letter from the President of the General Assembly announcing the HLM
During the run-up to UNGA 2024 and the HLM on AMR (15 Apr 2023 newsletter for details), I thought it would be useful to have a list of major reports. I am sure I am going to miss things (at least initially), so please drop me a note (john.rex@13.43.35.2) if you want to see something added to this list.
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Lifeline, the Musical Story of Penicillin: A Review
Dear All, Last week I went to New York City to see one of the opening performances of Lifeline, The Musical, the world’s first musical telling the story of penicillin, Sir Alexander Fleming, and the rise of antibiotic resistance! This was my first time seeing the production in its entirety and it did not disappoint. The timing
WHO: AMR Policy Brief and Preclinical pipeline data call
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UK Subscription model goes live! Value bands cover entire UK!
Dear All (with thanks to Kevin for leading on this newsletter and with a wonkish / long-read alert on this email … settle in for the ride!), Great news from TEAM UK! As of 12 August, the UK Subscription Program is no longer a pilot but is fully operational with an initial application deadline of
Needles and haystacks: Preclinical antibacterial pipeline review
Dear All, Just published in AAC is WHO’s updated review of the global preclinical pipeline. Here are the links you need to follow today’s discussion: The new WHO review: Gigante et al. “Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps”, https://doi.org/10.1128/aac.00535-24, AAC 2024. An excellent AAC podcast (overview webpage; YouTube video) discussing the WHO review. In